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Will Donovan Mitchell play tonight against the Indiana Pacers (Game 2, May 6, 2025)? Latest update on the Cleveland Cavaliers star's injury report

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The Cleveland Cavaliers face mounting pressure ahead of Game 2 against the Indiana Pacers, with Donovan Mitchell’s health becoming a major concern. After a surprising 121-112 loss in Game 1, the Cavaliers must regroup quickly, but Mitchell’s lingering issues could complicate their chances of evening the series.

Is Donovan Mitchell playing tonight against the Indiana Pacers? (Game 2, May 6, 2025)

Donovan Mitchell, who scored 33 points in Game 1 despite inefficient shooting, appeared to labor through stretches of the contest. While he isn’t listed on the official injury report, sources close to the team indicate he’s managing significant fatigue and minor soreness in his left knee—an issue that has bothered him intermittently this season. His ability to recover before Tuesday’s matchup will be critical for Cleveland’s offense.

Cleveland Cavaliers injury report for tonight’s game against the Indiana Pacers (May 6, 2025)


The Cavaliers are already dealing with multiple injuries, including Darius Garland (left toe sprain), Evan Mobley (ankle), and De’Andre Hunter (dislocated thumb), all listed as questionable.

Donovan Mitchell’s matchup against Andrew Nembhard will be key. In Game 1, Nembhard held Mitchell to just 1-of-10 shooting when defending him, a trend Cleveland must reverse. If Mitchell is limited, the Cavaliers will need bigger contributions from role players like Max Strus and Jarrett Allen.

Indiana Pacers injury report for tonight's game against the Cleveland Cavaliers (May 6, 2025)

For Indiana, staying healthy has been less of an issue, with only Isaiah Jackson ruled out for the season. Tyrese Haliburton and Pascal Siakam are fully available, giving the Pacers a clear edge if Cleveland’s stars are compromised.

When and where to watch the Cleveland Cavaliers play tonight against the Indiana Pacers (May 6, 2025)?

Game 2 tips off at 7:30 PM ET at Rocket Mortgage FieldHouse. The Cavaliers, as the East’s top seed, risk falling into an 0-2 hole if they can’t counter Indiana’s momentum—and Donovan Mitchell’s health may decide their fate.

Cleveland Cavaliers vs Indiana Pacers Game 1 overview

On May 4, 2025, the Indiana Pacers defeated the Cleveland Cavaliers 121–112 in Game 1 of the Eastern Conference semifinals. The Pacers dominated the majority of the game after taking an early 11-point lead in the first quarter. Aaron Nesmith's three-pointer halfway through the third quarter, which increased Indiana's advantage to 12 points and set off a Cavaliers comeback attempt, was a crucial moment.

Also read: Is Darius Garland playing tonight against the Indiana Pacers? Injury report reveals the Cleveland Cavaliers star’s status for Game 2 (May 6, 2025)

Tyrese Haliburton, who finished with 22 points, 13 assists, rebounds, three blocks, and a steal, led a decisive 20-10 run in the closing seconds, including a pivotal three-pointer and a block. Andrew Nembhard, who shot five out of six from three-point range, also had a stellar game with 23 points and six assists. The Cavaliers struggled with their three-point shooting, making only 9 of 38 shots from beyond the arc despite Donovan Mitchell's 33 points. The Pacers won on the road thanks to their balanced assault and excellent shooting.
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